Dimerization of Dengue Virus E Subunits Impacts Antibody Function and Domain Focus

Dengue virus (DENV) is responsible for the most prevalent and significant arthropod-borne viral infection of humans. The leading DENV vaccines are based on tetravalent live-attenuated virus platforms. In practice, it has been challenging to induce balanced and effective responses to each of the four...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Thomas, Ashlie, Thiono, Devina J., Kudlacek, Stephan T., Forsberg, John, Premkumar, Lakshmanane, Tian, Shaomin, Kuhlman, Brian, de Silva, Aravinda M., Metz, Stefan W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7459570/
https://ncbi.nlm.nih.gov/pubmed/32611757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00745-20
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