Reconstitution of an RNA Virus Replicase in Artificial Giant Unilamellar Vesicles Supports Full Replication and Provides Protection for the Double-Stranded RNA Replication Intermediate

Positive-strand RNA [(+)RNA] viruses are important pathogens of humans, animals, and plants and replicate inside host cells by coopting numerous host factors and subcellular membranes. To gain insights into the assembly of viral replicase complexes (VRCs) and dissect the roles of various lipids and...

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Vydáno v:J Virol
Hlavní autoři: Kovalev, Nikolay, Pogany, Judit, Nagy, Peter D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
Témata:
Genome Replication and Regulation of Viral Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7459549/
https://ncbi.nlm.nih.gov/pubmed/32641477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00267-20
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