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Reconstitution of an RNA Virus Replicase in Artificial Giant Unilamellar Vesicles Supports Full Replication and Provides Protection for the Double-Stranded RNA Replication Intermediate

Positive-strand RNA [(+)RNA] viruses are important pathogens of humans, animals, and plants and replicate inside host cells by coopting numerous host factors and subcellular membranes. To gain insights into the assembly of viral replicase complexes (VRCs) and dissect the roles of various lipids and...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Kovalev, Nikolay, Pogany, Judit, Nagy, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7459549/
https://ncbi.nlm.nih.gov/pubmed/32641477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00267-20
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