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Cyclophilin A Binds to the Viral RNA and Replication Proteins, Resulting in Inhibition of Tombusviral Replicase Assembly

Replication of plus-stranded RNA viruses is greatly affected by numerous host-encoded proteins that act as restriction factors. Cyclophilins, which are a large family of cellular prolyl isomerases, have been found to inhibit Tomato bushy stunt tombusvirus (TBSV) replication in a Saccharomyces cerevi...

詳細記述

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書誌詳細
主要な著者: Kovalev, Nikolay, Nagy, Peter D.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838255/
https://ncbi.nlm.nih.gov/pubmed/24089553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02101-13
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