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Cyclophilin A Binds to the Viral RNA and Replication Proteins, Resulting in Inhibition of Tombusviral Replicase Assembly
Replication of plus-stranded RNA viruses is greatly affected by numerous host-encoded proteins that act as restriction factors. Cyclophilins, which are a large family of cellular prolyl isomerases, have been found to inhibit Tomato bushy stunt tombusvirus (TBSV) replication in a Saccharomyces cerevi...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3838255/ https://ncbi.nlm.nih.gov/pubmed/24089553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02101-13 |
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