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The TPR Domain in the Host Cyp40-like Cyclophilin Binds to the Viral Replication Protein and Inhibits the Assembly of the Tombusviral Replicase

Replication of plus-stranded RNA viruses is greatly affected by numerous host-coded proteins acting either as susceptibility or resistance factors. Previous genome-wide screens and global proteomics approaches with Tomato bushy stunt tombusvirus (TBSV) in a yeast model host revealed the involvement...

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Hlavní autoři: Lin, Jing-Yi, Mendu, Venugopal, Pogany, Judit, Qin, Jun, Nagy, Peter D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276564/
https://ncbi.nlm.nih.gov/pubmed/22346747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002491
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