Reconstitution of an RNA Virus Replicase in Artificial Giant Unilamellar Vesicles Supports Full Replication and Provides Protection for the Double-Stranded RNA Replication Intermediate

Positive-strand RNA [(+)RNA] viruses are important pathogens of humans, animals, and plants and replicate inside host cells by coopting numerous host factors and subcellular membranes. To gain insights into the assembly of viral replicase complexes (VRCs) and dissect the roles of various lipids and...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Kovalev, Nikolay, Pogany, Judit, Nagy, Peter D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Genome Replication and Regulation of Viral Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7459549/
https://ncbi.nlm.nih.gov/pubmed/32641477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00267-20
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