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Crystallographic snapshots of UDP-glucuronic acid 4-epimerase ligand binding, rotation, and reduction

UDP-glucuronic acid is converted to UDP-galacturonic acid en route to a variety of sugar-containing metabolites. This reaction is performed by a NAD(+)-dependent epimerase belonging to the short-chain dehydrogenase/reductase family. We present several high-resolution crystal structures of the UDP-gl...

詳細記述

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書誌詳細
出版年:J Biol Chem
主要な著者: Iacovino, Luca Giacinto, Savino, Simone, Borg, Annika J. E., Binda, Claudia, Nidetzky, Bernd, Mattevi, Andrea
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7458814/
https://ncbi.nlm.nih.gov/pubmed/32661196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014692
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