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IDH-mutant gliomas harbor fewer regulatory T cells in humans and mice
The metabolic gene isocitrate dehydrogenase 1 (IDH1) is commonly mutated in lower grade glioma (LGG) and secondary glioblastoma (GBM). Regulatory T cells (Tregs) play a significant role in the suppression of antitumor immunity in human glioma. Given the importance of Tregs in the overall framework o...
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| Pubblicato in: | Oncoimmunology |
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| Autori principali: | , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7458656/ https://ncbi.nlm.nih.gov/pubmed/32923170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2020.1806662 |
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