The metabolic enzyme arginase-2 is a potential target for novel immune modulatory vaccines

One way that tumors evade immune destruction is through tumor and stromal cell expression of arginine-degrading enzyme arginase-2 (ARG2). Here we describe the existence of pro-inflammatory effector T-cells that recognize ARG2 and can directly target tumor and tumor-infiltrating cells. Using a librar...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncoimmunology
Egile Nagusiak: Weis-Banke, Stine Emilie, Hübbe, Mie Linder, Holmström, Morten Orebo, Jørgensen, Mia Aaboe, Bendtsen, Simone Kloch, Martinenaite, Evelina, Carretta, Marco, Svane, Inge Marie, Ødum, Niels, Pedersen, Ayako Wakatsuki, Met, Özcan, Madsen, Daniel Hargbøl, Andersen, Mads Hald
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2020
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7458644/
https://ncbi.nlm.nih.gov/pubmed/32923127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2020.1771142
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