Dexamethasone premedication suppresses vaccine-induced immune responses against cancer

Glucocorticosteroids (GCS) have an established role in oncology and are administered to cancer patients in routine clinical care and in drug development trials as co-medication. Given their strong immune-suppressive activity, GCS may interfere with immune-oncology drugs. We are developing a therapeu...

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發表在:Oncoimmunology
Main Authors: Vormehr, Mathias, Lehar, Sophie, Kranz, Lena M., Tahtinen, Siri, Oei, Yoko, Javinal, Vincent, Delamarre, Lélia, Walzer, Kerstin C., Diken, Mustafa, Kreiter, Sebastian, Mellman, Ira, Sahin, Ugur, Schartner, Jill M., Türeci, Özlem
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2020
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7458619/
https://ncbi.nlm.nih.gov/pubmed/32923115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2020.1758004
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