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Relating SMCHD1 structure to its function in epigenetic silencing

The structural maintenance of chromosomes hinge domain containing protein 1 (SMCHD1) is a large multidomain protein involved in epigenetic gene silencing. Variations in the SMCHD1 gene are associated with two debilitating human disorders, facioscapulohumeral muscular dystrophy (FSHD) and Bosma arhin...

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Bibliografische gegevens
Gepubliceerd in:Biochem Soc Trans
Hoofdauteurs: Gurzau, Alexandra D., Blewitt, Marnie E., Czabotar, Peter E., Murphy, James M., Birkinshaw, Richard W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Portland Press Ltd. 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7458401/
https://ncbi.nlm.nih.gov/pubmed/32779700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20200242
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