Genome-wide binding and mechanistic analyses of Smchd1-mediated epigenetic regulation

Structural maintenance of chromosomes flexible hinge domain containing 1 (Smchd1) is an epigenetic repressor with described roles in X inactivation and genomic imprinting, but Smchd1 is also critically involved in the pathogenesis of facioscapulohumeral dystrophy. The underlying molecular mechanism...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Chen, Kelan, Hu, Jiang, Moore, Darcy L., Liu, Ruijie, Kessans, Sarah A., Breslin, Kelsey, Lucet, Isabelle S., Keniry, Andrew, Leong, Huei San, Parish, Clare L., Hilton, Douglas J., Lemmers, Richard J. L. F., van der Maarel, Silvère M., Czabotar, Peter E., Dobson, Renwick C. J., Ritchie, Matthew E., Kay, Graham F., Murphy, James M., Blewitt, Marnie E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2015
Gaiak:
PNAS Plus
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500281/
https://ncbi.nlm.nih.gov/pubmed/26091879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1504232112
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