Genome-wide binding and mechanistic analyses of Smchd1-mediated epigenetic regulation

Structural maintenance of chromosomes flexible hinge domain containing 1 (Smchd1) is an epigenetic repressor with described roles in X inactivation and genomic imprinting, but Smchd1 is also critically involved in the pathogenesis of facioscapulohumeral dystrophy. The underlying molecular mechanism...

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Enregistré dans:
Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Chen, Kelan, Hu, Jiang, Moore, Darcy L., Liu, Ruijie, Kessans, Sarah A., Breslin, Kelsey, Lucet, Isabelle S., Keniry, Andrew, Leong, Huei San, Parish, Clare L., Hilton, Douglas J., Lemmers, Richard J. L. F., van der Maarel, Silvère M., Czabotar, Peter E., Dobson, Renwick C. J., Ritchie, Matthew E., Kay, Graham F., Murphy, James M., Blewitt, Marnie E.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2015
Sujets:
PNAS Plus
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500281/
https://ncbi.nlm.nih.gov/pubmed/26091879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1504232112
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