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Reduced dosage of the modifiers of epigenetic reprogramming Dnmt1, Dnmt3L, SmcHD1 and Foxo3a has no detectable effect on mouse telomere length in vivo

Studies carried out in cultured cells have implicated modifiers of epigenetic reprogramming in the regulation of telomere length, reporting elongation in cells that were null for DNA methyltransferase DNA methyltransferase 1 (Dnmt1), both de novo DNA methyltransferases, Dnmt3a and Dnmt3b or various...

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Detalhes bibliográficos
Main Authors: Roberts, Amity R., Blewitt, Marnie E., Youngson, Neil A., Whitelaw, Emma, Chong, Suyinn
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140923/
https://ncbi.nlm.nih.gov/pubmed/21553025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-011-0318-9
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