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Novel Compound Heterozygous Mutations in CRTAP Cause Rare Autosomal Recessive Osteogenesis Imperfecta

Whole-exome sequencing (WES) has advantages over the traditional molecular test by screening 20,000 genes simultaneously and has become an invaluable tool for genetic diagnosis in clinical practice. Here, we reported a family with a child and a fetus presenting undiagnosed skeletal dysplasia phenoty...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Tang, Yen-An, Wang, Lin-Yen, Chang, Chiao-May, Lee, I-Wen, Tsai, Wen-Hui, Sun, H. Sunny
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7457090/
https://ncbi.nlm.nih.gov/pubmed/32922437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00897
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