Tendon and motor phenotypes in the Crtap(-/-) mouse model of recessive osteogenesis imperfecta

Osteogenesis imperfecta (OI) is characterized by short stature, skeletal deformities, low bone mass, and motor deficits. A subset of OI patients also present with joint hypermobility; however, the role of tendon dysfunction in OI pathogenesis is largely unknown. Using the Crtap(-/-) mouse model of s...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Grol, Matthew William, Haelterman, Nele A, Lim, Joohyun, Munivez, Elda M, Archer, Marilyn, Hudson, David M, Tufa, Sara F, Keene, Douglas R, Lei, Kevin, Park, Dongsu, Kuzawa, Cole D, Ambrose, Catherine G, Eyre, David R, Lee, Brendan H
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2021
Assuntos:
Genetics and Genomics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8186905/
https://ncbi.nlm.nih.gov/pubmed/34036937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.63488
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