Effect of ApoE isoforms on mitochondria in Alzheimer disease

OBJECTIVE: To test the hypothesis that ApoE isoforms affect mitochondrial structure and function that are related to cognitive impairment in Alzheimer disease (AD), we systematically investigated the effects of ApoE isoforms on mitochondrial biogenesis and dynamics, oxidative stress, synapses, and c...

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Publicado en:Neurology
Main Authors: Yin, Junxiang, Reiman, Eric M., Beach, Thomas G., Serrano, Geidy E., Sabbagh, Marwan N., Nielsen, Megan, Caselli, Richard J., Shi, Jiong
Formato: Artigo
Idioma:Inglês
Publicado: Lippincott Williams & Wilkins 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455369/
https://ncbi.nlm.nih.gov/pubmed/32457210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000009582
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