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Effect of ApoE isoforms on mitochondria in Alzheimer disease

OBJECTIVE: To test the hypothesis that ApoE isoforms affect mitochondrial structure and function that are related to cognitive impairment in Alzheimer disease (AD), we systematically investigated the effects of ApoE isoforms on mitochondrial biogenesis and dynamics, oxidative stress, synapses, and c...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neurology
Prif Awduron: Yin, Junxiang, Reiman, Eric M., Beach, Thomas G., Serrano, Geidy E., Sabbagh, Marwan N., Nielsen, Megan, Caselli, Richard J., Shi, Jiong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Lippincott Williams & Wilkins 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455369/
https://ncbi.nlm.nih.gov/pubmed/32457210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000009582
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