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Integrin nanoclusters can bridge thin matrix fibres to form cell–matrix adhesions

Integrin-mediated cell–matrix adhesions are key to sensing the geometry and rigidity of extracellular environments and influence vital cellular processes. Invivo, the extracellular matrix is composed of fibrous arrays. To understand the fibre geometries that are required for adhesion formation, we p...

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Detalhes bibliográficos
Publicado no:Nat Mater
Main Authors: Changede, Rishita, Cai, Haogang, Wind, Shalom J., Sheetz, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455205/
https://ncbi.nlm.nih.gov/pubmed/31477904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41563-019-0460-y
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