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Changes in membrane sphingolipid composition modulate dynamics and adhesion of integrin nanoclusters

Sphingolipids are essential constituents of the plasma membrane (PM) and play an important role in signal transduction by modulating clustering and dynamics of membrane receptors. Changes in lipid composition are therefore likely to influence receptor organisation and function, but how this precisel...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Eich, Christina, Manzo, Carlo, Keijzer, Sandra de, Bakker, Gert-Jan, Reinieren-Beeren, Inge, García-Parajo, Maria F., Cambi, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751618/
https://ncbi.nlm.nih.gov/pubmed/26869100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20693
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