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N-glycan mediated adhesion strengthening during pathogen-receptor binding revealed by cell-cell force spectroscopy

Glycan-protein lateral interactions have gained increased attention as important modulators of receptor function, by regulating surface residence time and endocytosis of membrane glycoproteins. The pathogen-recognition receptor DC-SIGN is highly expressed at the membrane of antigen-presenting dendri...

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Publicat a:Sci Rep
Autors principals: te Riet, Joost, Joosten, Ben, Reinieren-Beeren, Inge, Figdor, Carl G., Cambi, Alessandra
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5532264/
https://ncbi.nlm.nih.gov/pubmed/28751750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07220-w
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