The Neck Region of the C-type Lectin DC-SIGN Regulates Its Surface Spatiotemporal Organization and Virus-binding Capacity on Antigen-presenting Cells

The C-type lectin DC-SIGN expressed on dendritic cells (DCs) facilitates capture and internalization of a plethora of different pathogens. Although it is known that DC-SIGN organizes in nanoclusters at the surface of DCs, the molecular mechanisms responsible for this well defined nanopatterning and...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Manzo, Carlo, Torreno-Pina, Juan A., Joosten, Ben, Reinieren-Beeren, Inge, Gualda, Emilio J., Loza-Alvarez, Pablo, Figdor, Carl G., Garcia-Parajo, Maria F., Cambi, Alessandra
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2012
Pynciau:
Membrane Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493935/
https://ncbi.nlm.nih.gov/pubmed/23019323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.380121
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