Downregulating CREBBP inhibits proliferation and cell cycle progression and induces daunorubicin resistance in leukemia cells

Low expression levels of CREB-binding protein (CREBBP) have been demonstrated to be associated with high minimal residual disease at the end of induction therapy and adverse long-term outcomes in pediatric patients with acute lymphoblastic leukemia (ALL). However, the effect of low CREBBP expression...

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Publicado en:Mol Med Rep
Autores principales: Gao, Chao, Liu, Shu-Guang, Lu, Wen-Ting, Yue, Zhi-Xia, Zhao, Xiao-Xi, Xing, Tian-Yu, Chen, Zhen-Ping, Zheng, Hu-Yong, Li, Zhi-Gang
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2020
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7453649/
https://ncbi.nlm.nih.gov/pubmed/32945392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11347
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