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β-catenin promotes MTX resistance of leukemia cells by down-regulating FPGS expression via NF-κB
BACKGROUND: Aberrant activation of β-catenin has been shown to play important roles in the chemoresistance of acute lymphoblastic leukemia (ALL), but the involvement and mechanism of β-catenin in methotrexate (MTX) resistance is poorly understood. In the present study, we demonstrate a critical role...
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| Publicado no: | Cancer Cell Int |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7313175/ https://ncbi.nlm.nih.gov/pubmed/32587478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01364-y |
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