RNA-binding proteins Musashi and tau soluble aggregates initiate nuclear dysfunction

Oligomeric assemblies of tau and the RNA-binding proteins (RBPs) Musashi (MSI) are reported in Alzheimer’s disease (AD). However, the role of MSI and tau interaction in their aggregation process and its effects are nor clearly known in neurodegenerative diseases. Here, we investigated the expression...

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Udgivet i:Nat Commun
Main Authors: Montalbano, Mauro, McAllen, Salome, Puangmalai, Nicha, Sengupta, Urmi, Bhatt, Nemil, Johnson, Omar D., Kharas, Michael G., Kayed, Rakez
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7453003/
https://ncbi.nlm.nih.gov/pubmed/32855391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18022-6
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