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RNA-binding proteins Musashi and tau soluble aggregates initiate nuclear dysfunction

Oligomeric assemblies of tau and the RNA-binding proteins (RBPs) Musashi (MSI) are reported in Alzheimer’s disease (AD). However, the role of MSI and tau interaction in their aggregation process and its effects are nor clearly known in neurodegenerative diseases. Here, we investigated the expression...

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Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Montalbano, Mauro, McAllen, Salome, Puangmalai, Nicha, Sengupta, Urmi, Bhatt, Nemil, Johnson, Omar D., Kharas, Michael G., Kayed, Rakez
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7453003/
https://ncbi.nlm.nih.gov/pubmed/32855391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18022-6
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