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Glucocorticoid Priming of Nonviral Gene Delivery to hMSCs Increases Transfection by Reducing Induced Stresses

Human mesenchymal stem cells (hMSCs) are under study for cell and gene therapeutics because of their immunomodulatory and regenerative properties. Safe and efficient gene delivery could increase hMSC clinical potential by enabling expression of transgenes for control over factor production, behavior...

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Detalles Bibliográficos
Publicado en:Mol Ther Methods Clin Dev
Main Authors: Hamann, Andrew, Kozisek, Tyler, Broad, Kelly, Pannier, Angela K.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Gene & Cell Therapy 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7452153/
https://ncbi.nlm.nih.gov/pubmed/32913879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.07.014
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