High-throughput screening of clinically approved drugs that prime nonviral gene delivery to human Mesenchymal stem cells

BACKGROUND: Human mesenchymal stem cells (hMSCs) are intensely researched for applications in cell therapeutics due to their unique properties, however, intrinsic therapeutic properties of hMSCs could be enhanced by genetic modification. Viral transduction is efficient, but suffers from safety issue...

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Detalhes bibliográficos
Publicado no:J Biol Eng
Main Authors: Kozisek, Tyler, Hamann, Andrew, Nguyen, Albert, Miller, Michael, Plautz, Sarah, Pannier, Angela K.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7238544/
https://ncbi.nlm.nih.gov/pubmed/32467728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-020-00238-1
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