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Glucocorticoid Priming of Nonviral Gene Delivery to hMSCs Increases Transfection by Reducing Induced Stresses

Human mesenchymal stem cells (hMSCs) are under study for cell and gene therapeutics because of their immunomodulatory and regenerative properties. Safe and efficient gene delivery could increase hMSC clinical potential by enabling expression of transgenes for control over factor production, behavior...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Hamann, Andrew, Kozisek, Tyler, Broad, Kelly, Pannier, Angela K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7452153/
https://ncbi.nlm.nih.gov/pubmed/32913879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.07.014
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