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Generation and characterization of keap1a- and keap1b-knockout zebrafish
The Keap1–Nrf2 pathway is an evolutionarily conserved mechanism that protects cells from oxidative stress and electrophiles. Under homeostatic conditions, Keap1 interacts with Nrf2 and leads to its rapid proteasomal degradation, but when cells are exposed to oxidative stress/electrophiles, Keap1 sen...
Gorde:
| Argitaratua izan da: | Redox Biol |
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| Egile Nagusiak: | , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Elsevier
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7452054/ https://ncbi.nlm.nih.gov/pubmed/32828016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101667 |
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