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Splicing- and demethylase-independent functions of LSD1 in zebrafish primitive hematopoiesis

LSD1/KDM1A is a widely conserved lysine-specific demethylase that removes methyl groups from methylated proteins, mainly histone H3. We previously isolated the zebrafish LSD1 gene and demonstrated that it is required for primitive hematopoiesis. Recently, a neuron-specific splicing variant of LSD1 w...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Tamaoki, Junya, Takeuchi, Miki, Abe, Ryo, Kaneko, Hiroshi, Wada, Taeko, Hino, Shinjiro, Nakao, Mitsuyoshi, Furukawa, Yusuke, Kobayashi, Makoto
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7244555/
https://ncbi.nlm.nih.gov/pubmed/32444613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65428-9
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