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Total Synthesis of (+)-Raputindole A: An Iridium-Catalyzed Cyclization Approach

[Image: see text] This work describes the total synthesis of raputindole A (1) through a convergent approach that features (1) an iridium-catalyzed cyclization to assemble the tricyclic core of the northern part, (2) enzymatic resolution to secure the preparation of an enantiomerically pure benzylic...

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Publicado en:Org Lett
Main Authors: Regueira, Juliana L. L. F., Silva, Luiz F., Pilli, Ronaldo A.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2020
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7450706/
https://ncbi.nlm.nih.gov/pubmed/32806179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.0c01943
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