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Total Synthesis of (+)-Complanadine A Using an Iridium-Catalyzed Pyridine C-H Functionalization

Total synthesis of the Lycopodium alkaloid complanadine A, which is an unsymmetrical dimer of lycodine, was achieved by exploiting a common tetracyclic precursor. Key to the success of the synthesis was the development of a late-stage site-selective C-H functionalization of a pyridine moiety to arri...

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Detalhes bibliográficos
Main Authors: Fischer, Daniel F., Sarpong, Richmond
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867450/
https://ncbi.nlm.nih.gov/pubmed/20387895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja101893b
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