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Total Synthesis of Cyclopiamide A Using Palladium-Catalyzed Domino Cyclization

Total synthesis of cyclopiamide A was accomplished using a palladium-catalyzed domino cyclization. Three rings in the tetracyclic skeleton of cyclopiamide A were constructed in a one-step domino reaction incorporating double carbopalladation and C-H activation.

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Park, Sunhwa, Shin, Kye Jung, Seo, Jae Hong
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7660198/
https://ncbi.nlm.nih.gov/pubmed/33113968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25214903
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