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A systematic evaluation of single-cell RNA-sequencing imputation methods

BACKGROUND: The rapid development of single-cell RNA-sequencing (scRNA-seq) technologies has led to the emergence of many methods for removing systematic technical noises, including imputation methods, which aim to address the increased sparsity observed in single-cell data. Although many imputation...

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Veröffentlicht in:Genome Biol
Hauptverfasser: Hou, Wenpin, Ji, Zhicheng, Ji, Hongkai, Hicks, Stephanie C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7450705/
https://ncbi.nlm.nih.gov/pubmed/32854757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02132-x
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