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Single-cell ATAC-seq signal extraction and enhancement with SCATE

Single-cell sequencing assay for transposase-accessible chromatin (scATAC-seq) is the state-of-the-art technology for analyzing genome-wide regulatory landscapes in single cells. Single-cell ATAC-seq data are sparse and noisy, and analyzing such data is challenging. Existing computational methods ca...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Ji, Zhicheng, Zhou, Weiqiang, Hou, Wenpin, Ji, Hongkai
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7333383/
https://ncbi.nlm.nih.gov/pubmed/32620137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02075-3
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