Comprehensive analysis of single cell ATAC-seq data with SnapATAC

Identification of the cis-regulatory elements controlling cell-type specific gene expression patterns is essential for understanding the origin of cellular diversity. Conventional assays to map regulatory elements via open chromatin analysis of primary tissues is hindered by sample heterogeneity. Si...

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Udgivet i:Nat Commun
Main Authors: Fang, Rongxin, Preissl, Sebastian, Li, Yang, Hou, Xiaomeng, Lucero, Jacinta, Wang, Xinxin, Motamedi, Amir, Shiau, Andrew K., Zhou, Xinzhu, Xie, Fangming, Mukamel, Eran A., Zhang, Kai, Zhang, Yanxiao, Behrens, M. Margarita, Ecker, Joseph R., Ren, Bing
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7910485/
https://ncbi.nlm.nih.gov/pubmed/33637727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21583-9
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