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The folding and unfolding behavior of ribonuclease H on the ribosome

The health of a cell depends on accurate translation and proper protein folding, whereas misfolding can lead to aggregation and disease. The first opportunity for a protein to fold occurs during translation, when the ribosome and surrounding environment can affect the nascent chain energy landscape....

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Jensen, Madeleine K., Samelson, Avi J., Steward, Annette, Clarke, Jane, Marqusee, Susan
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7450101/
https://ncbi.nlm.nih.gov/pubmed/32527724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013909
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