The human papillomavirus E6 protein targets apoptosis-inducing factor (AIF) for degradation

Oncoprotein E6 of high-risk human papillomavirus (HPV) plays a critical role in inducing cell immortalization and malignancy. E6 downregulates caspase-dependent pathway through the degradation of p53. However, the effect of HPV E6 on other pathways is still under investigation. In the present study,...

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Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Shimada, Masaru, Yamashita, Akio, Saito, Manami, Ichino, Motohide, Kinjo, Takao, Mizuki, Nobuhisa, Klinman, Dennis M., Okuda, Kenji
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7450093/
https://ncbi.nlm.nih.gov/pubmed/32848167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71134-3
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