Nondegradative Ubiquitination of Apoptosis Inducing Factor (AIF) by X-Linked Inhibitor of Apoptosis at a Residue Critical for AIF-Mediated Chromatin Degradation

Apoptosis inducing factor (AIF) is a mediator of caspase-independent cell death that is also necessary for mitochondrial energy production. How these seemingly opposite cellular functions of AIF are controlled is poorly understood. X-linked inhibitor of apoptosis (XIAP) is an endogenous inhibitor of...

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Publicado en:Biochemistry
Main Authors: Lewis, Eric M., Wilkinson, Amanda S., Davis, Nicole Y., Horita, David A., Wilkinson, John C.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477681/
https://ncbi.nlm.nih.gov/pubmed/22103349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201483g
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