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Nrf2/HO-1 mediates the neuroprotective effects of pramipexole by attenuating oxidative damage and mitochondrial perturbation after traumatic brain injury in rats

Pramipexole (PPX), a D2-like receptor agonist, is generally used in the treatment of Parkinson's disease and restless leg syndrome. Its neuroprotective effects have been shown against various neurological disorders. Recent research work has demonstrated that PPX exerts neuroprotection through m...

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Publicat a:Dis Model Mech
Autors principals: Salman, Mohd., Tabassum, Heena, Parvez, Suhel
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449795/
https://ncbi.nlm.nih.gov/pubmed/32540990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.045021
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