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Nrf2/HO-1 mediates the neuroprotective effects of pramipexole by attenuating oxidative damage and mitochondrial perturbation after traumatic brain injury in rats

Pramipexole (PPX), a D2-like receptor agonist, is generally used in the treatment of Parkinson's disease and restless leg syndrome. Its neuroprotective effects have been shown against various neurological disorders. Recent research work has demonstrated that PPX exerts neuroprotection through m...

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Dettagli Bibliografici
Pubblicato in:Dis Model Mech
Autori principali: Salman, Mohd., Tabassum, Heena, Parvez, Suhel
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449795/
https://ncbi.nlm.nih.gov/pubmed/32540990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.045021
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