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Nrf2/HO-1 mediates the neuroprotective effects of pramipexole by attenuating oxidative damage and mitochondrial perturbation after traumatic brain injury in rats

Pramipexole (PPX), a D2-like receptor agonist, is generally used in the treatment of Parkinson's disease and restless leg syndrome. Its neuroprotective effects have been shown against various neurological disorders. Recent research work has demonstrated that PPX exerts neuroprotection through m...

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Detalles Bibliográficos
Publicado en:Dis Model Mech
Autores principales: Salman, Mohd., Tabassum, Heena, Parvez, Suhel
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists Ltd 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449795/
https://ncbi.nlm.nih.gov/pubmed/32540990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.045021
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