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Model-based evaluation of the microhemodynamic effects of PEGylated HBOC molecules in the rat brain cortex: a laser speckle imaging study

Hemoglobin-based oxygen carriers (HBOCs) were developed with the aim of substituting transfusions in emergency events. However, they exhibit adverse events, such as nitric oxide (NO) scavenging, vasoactivity, enhanced platelet aggregation, presently hampering their clinical application. The impact o...

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Vydáno v:Biomed Opt Express
Hlavní autoři: Portörő, István, Mukli, Péter, Kocsis, László, Hermán, Péter, Caccia, Dario, Perrella, Michele, Mozzarelli, Andrea, Ronda, Luca, Mathe, Domokos, Eke, Andras
Médium: Artigo
Jazyk:Inglês
Vydáno: Optical Society of America 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449705/
https://ncbi.nlm.nih.gov/pubmed/32923034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/BOE.388089
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