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Model-based evaluation of the microhemodynamic effects of PEGylated HBOC molecules in the rat brain cortex: a laser speckle imaging study

Hemoglobin-based oxygen carriers (HBOCs) were developed with the aim of substituting transfusions in emergency events. However, they exhibit adverse events, such as nitric oxide (NO) scavenging, vasoactivity, enhanced platelet aggregation, presently hampering their clinical application. The impact o...

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Detalhes bibliográficos
Publicado no:Biomed Opt Express
Main Authors: Portörő, István, Mukli, Péter, Kocsis, László, Hermán, Péter, Caccia, Dario, Perrella, Michele, Mozzarelli, Andrea, Ronda, Luca, Mathe, Domokos, Eke, Andras
Formato: Artigo
Idioma:Inglês
Publicado em: Optical Society of America 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449705/
https://ncbi.nlm.nih.gov/pubmed/32923034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/BOE.388089
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