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Model-based evaluation of the microhemodynamic effects of PEGylated HBOC molecules in the rat brain cortex: a laser speckle imaging study

Hemoglobin-based oxygen carriers (HBOCs) were developed with the aim of substituting transfusions in emergency events. However, they exhibit adverse events, such as nitric oxide (NO) scavenging, vasoactivity, enhanced platelet aggregation, presently hampering their clinical application. The impact o...

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Библиографические подробности
Опубликовано в: :Biomed Opt Express
Главные авторы: Portörő, István, Mukli, Péter, Kocsis, László, Hermán, Péter, Caccia, Dario, Perrella, Michele, Mozzarelli, Andrea, Ronda, Luca, Mathe, Domokos, Eke, Andras
Формат: Artigo
Язык:Inglês
Опубликовано: Optical Society of America 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449705/
https://ncbi.nlm.nih.gov/pubmed/32923034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/BOE.388089
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