A key role for the novel coronary artery disease gene JCAD in atherosclerosis via shear stress mechanotransduction

AIMS: Genome-wide association studies (GWAS) have consistently identified an association between coronary artery disease (CAD) and a locus on chromosome 10 containing a single gene, JCAD (formerly KIAA1462). However, little is known about the mechanism by which JCAD could influence the development o...

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Vydáno v:Cardiovasc Res
Hlavní autoři: Douglas, Gillian, Mehta, Vedanta, Al Haj Zen, Ayman, Akoumianakis, Ioannis, Goel, Anuj, Rashbrook, Victoria S, Trelfa, Lucy, Donovan, Lucy, Drydale, Edward, Chuaiphichai, Surawee, Antoniades, Charalambos, Watkins, Hugh, Kyriakou, Theodosios, Tzima, Ellie, Channon, Keith M
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Review Series from the Naples 2019 Joint Meeting of the ESC Working Groups on Myocardial Function and Cellular Biology of the Heart
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449560/
https://ncbi.nlm.nih.gov/pubmed/31584065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvz263
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