The FDA-Approved Drug Nelfinavir Inhibits Lytic Cell-Free but Not Cell-Associated Nonlytic Transmission of Human Adenovirus

Adenoviruses (AdVs) are prevalent and give rise to chronic and recurrent disease. Human AdV (HAdV) species B and C, such as HAdV-C2, -C5, and -B14, cause respiratory disease and constitute a health threat for immunocompromised individuals. HAdV-Cs are well known for lysing cells owing to the E3 CR1-...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Georgi, Fanny, Andriasyan, Vardan, Witte, Robert, Murer, Luca, Hemmi, Silvio, Yu, Lisa, Grove, Melanie, Meili, Nicole, Kuttler, Fabien, Yakimovich, Artur, Turcatti, Gerardo, Greber, Urs F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449217/
https://ncbi.nlm.nih.gov/pubmed/32601166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01002-20
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