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A high-content image-based drug screen of clinical compounds against cell transmission of adenovirus

Human adenoviruses (HAdVs) are fatal to immuno-suppressed individuals, but no effective anti-HAdV therapy is available. Here, we present a novel image-based high-throughput screening (HTS) platform, which scores the full viral replication cycle from virus entry to dissemination of progeny and second...

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Detalhes bibliográficos
Publicado no:Sci Data
Main Authors: Georgi, Fanny, Kuttler, Fabien, Murer, Luca, Andriasyan, Vardan, Witte, Robert, Yakimovich, Artur, Turcatti, Gerardo, Greber, Urs F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423605/
https://ncbi.nlm.nih.gov/pubmed/32788590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41597-020-00604-0
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