Candida glabrata Transcription Factor Rpn4 Mediates Fluconazole Resistance through Regulation of Ergosterol Biosynthesis and Plasma Membrane Permeability

The ability to acquire azole resistance is an emblematic trait of the fungal pathogen Candida glabrata. Understanding the molecular basis of azole resistance in this pathogen is crucial for designing more suitable therapeutic strategies. This study shows that the C. glabrata transcription factor (TF...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Antimicrob Agents Chemother
Egile Nagusiak: Pais, Pedro, Califórnia, Raquel, Galocha, Mónica, Viana, Romeu, Ola, Mihaela, Cavalheiro, Mafalda, Takahashi-Nakaguchi, Azusa, Chibana, Hiroji, Butler, Geraldine, Teixeira, Miguel C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2020
Gaiak:
Mechanisms of Resistance
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449212/
https://ncbi.nlm.nih.gov/pubmed/32571817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00554-20
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